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Chondrogenic differentiation of human mesenchymal stem cell aggregates via controlled release of TGF-β1 from incorporated polymer microspheres

Aggregate culture is a useful method for inducing chondrogenic differentiation of human mesenchymal stem cells (hMSC) in a three-dimensional in vitro culture environment. Conventional aggregate culture, however, typically requires repeated growth factor supplementation during media changes, which is...

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Bibliographic Details
Main Authors: Solorio, Loran D., Fu, Andrew S., Hernández-Irizarry, Roberto, Alsberg, Eben
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549267/
https://ncbi.nlm.nih.gov/pubmed/19322820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.32440
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