Inhibition of Nicotinamide Phosphoribosyltransferase Reduces Neutrophil-Mediated Injury in Myocardial Infarction

Aims: Nicotinamide phosphoribosyltransferase (Nampt) is a key enzyme for nicotinamide adenine dinucleotide (NAD(+)) biosynthesis, and recent evidence indicates its role in inflammatory processes. Here, we investigated the potential effects of pharmacological Nampt inhibition with FK866 in a mouse my...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Montecucco, Fabrizio, Bauer, Inga, Braunersreuther, Vincent, Bruzzone, Santina, Akhmedov, Alexander, Lüscher, Thomas F., Speer, Timo, Poggi, Alessandro, Mannino, Elena, Pelli, Graziano, Galan, Katia, Bertolotto, Maria, Lenglet, Sébastien, Garuti, Anna, Montessuit, Christophe, Lerch, René, Pellieux, Corinne, Vuilleumier, Nicolas, Dallegri, Franco, Mage, Jacqueline, Sebastian, Carlos, Mostoslavsky, Raul, Gayet-Ageron, Angèle, Patrone, Franco, Mach, François, Nencioni, Alessio
التنسيق: Artigo
اللغة:Inglês
منشور في: Mary Ann Liebert, Inc. 2013
الموضوعات:
Forum Original Research Communication
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549207/
https://ncbi.nlm.nih.gov/pubmed/22452634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4487
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