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Essential role of postsynaptic NMDA receptors in developmental refinement of excitatory synapses
Neurons in the brains of newborns are usually connected with many other neurons through weak synapses. This early pattern of connectivity is refined through pruning of many immature connections and strengthening of the remaining ones. NMDA receptors (NMDARs) are essential for the development of exci...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
National Academy of Sciences
2013
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549111/ https://ncbi.nlm.nih.gov/pubmed/23277569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212971110 |
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