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Structural basis for the activation mechanism of the PlcR virulence regulator by the quorum-sensing signal peptide PapR

The quorum-sensing regulator PlcR is the master regulator of most known virulence factors in Bacillus cereus. It is a helix-turn-helix (HTH)-type transcription factor activated upon binding of its cognate signaling peptide PapR on a tetratricopeptide repeat-type regulatory domain. The structural and...

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Bibliographische Detailangaben
Hauptverfasser: Grenha, Rosa, Slamti, Leyla, Nicaise, Magali, Refes, Yacine, Lereclus, Didier, Nessler, Sylvie
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549096/
https://ncbi.nlm.nih.gov/pubmed/23277548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213770110
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