Identification of an essential endogenous regulator of blood–brain barrier integrity, and its pathological and therapeutic implications

The blood–brain barrier (BBB), a critical guardian of communication between the periphery and the brain, is frequently compromised in neurological diseases such as multiple sclerosis (MS), resulting in the inappropriate passage of molecules and leukocytes into the brain. Here we show that the glucoc...

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Hlavní autoři: Cristante, Enrico, McArthur, Simon, Mauro, Claudio, Maggioli, Elisa, Romero, Ignacio A., Wylezinska-Arridge, Marzena, Couraud, Pierre O., Lopez-Tremoleda, Jordi, Christian, Helen C., Weksler, Babette B., Malaspina, Andrea, Solito, Egle
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
Feature Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549094/
https://ncbi.nlm.nih.gov/pubmed/23277546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209362110
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