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Cellular steatosis in ethanol oxidizing-HepG2 cells is partially controlled by the transcription factor, early growth response-1

Recent studies have shown that the transcription factor early growth response-1 (Egr-1) regulates ethanol-induced fatty liver. However, the mechanism(s) through which ethanol oxidation controls Egr-1 is unknown. Here, using recombinant hepatoma (HepG2; VL-17A) cells that metabolize ethanol, we show...

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Detalhes bibliográficos
Main Authors: Thomes, Paul G., Osna, Natalia A., Davis, John S., Donohue, Terrence M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549023/
https://ncbi.nlm.nih.gov/pubmed/23103837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2012.10.002
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