CYP2D6 Metabolism and Patient Outcome in the Austrian Breast and Colorectal Cancer Study Group Trial (ABCSG) 8

BACKGROUND: Controversy exists regarding CYP2D6 genotype and tamoxifen efficacy. METHODS: A matched case-control study was conducted utilizing the Austrian Breast and Colorectal Cancer Study Group Trial 8 that randomized post-menopausal women with estrogen receptor positive breast cancer to tamoxife...

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Hauptverfasser: Goetz, Matthew P., Suman, Vera J., Hoskin, Tanya L., Gnant, Michael, Filipits, Martin, Safgren, Stephanie L., Kuffel, Mary, Jakesz, Raimund, Rudas, Margaretha, Greil, Richard, Dietze, Otto, Lang, Alois, Offner, Felix, Reynolds, Carol A., Weinshilboum, Richard M., Ames, Matthew M., Ingle, James N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548984/
https://ncbi.nlm.nih.gov/pubmed/23213055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2153
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