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CYP2D6 Metabolism and Patient Outcome in the Austrian Breast and Colorectal Cancer Study Group Trial (ABCSG) 8

BACKGROUND: Controversy exists regarding CYP2D6 genotype and tamoxifen efficacy. METHODS: A matched case-control study was conducted utilizing the Austrian Breast and Colorectal Cancer Study Group Trial 8 that randomized post-menopausal women with estrogen receptor positive breast cancer to tamoxife...

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Hlavní autoři: Goetz, Matthew P., Suman, Vera J., Hoskin, Tanya L., Gnant, Michael, Filipits, Martin, Safgren, Stephanie L., Kuffel, Mary, Jakesz, Raimund, Rudas, Margaretha, Greil, Richard, Dietze, Otto, Lang, Alois, Offner, Felix, Reynolds, Carol A., Weinshilboum, Richard M., Ames, Matthew M., Ingle, James N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548984/
https://ncbi.nlm.nih.gov/pubmed/23213055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2153
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