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Pharmacokinetics of 2 Formulations of Buprenorphine in Macaques (Macaca mulatta and Macaca fascicularis)

Buprenorphine is the cornerstone of pain management in nonhuman primates, but the pharmacokinetics of this widely used drug are unknown. The purpose of this study was to evaluate the pharmacokinetic profiles of buprenorphine (0.01 and 0.03 mg/kg IM) and sustained-release buprenorphine (0.2 mg/kg SC)...

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Autors principals: Nunamaker, Elizabeth A, Halliday, Lisa C, Moody, David E, Fang, Wenfang B, Lindeblad, Matthew, Fortman, Jeffrey D
Format: Artigo
Idioma:Inglês
Publicat: American Association for Laboratory Animal Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548201/
https://ncbi.nlm.nih.gov/pubmed/23562033
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