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Positional Cloning Reveals Strain-Dependent Expression of Trim16 to Alter Susceptibility to Bleomycin-Induced Pulmonary Fibrosis in Mice
Pulmonary fibrosis is a disease of significant morbidity, with no effective therapeutics and an as yet incompletely defined genetic basis. The chemotherapeutic agent bleomycin induces pulmonary fibrosis in susceptible C57BL/6J mice but not in mice of the C3H/HeJ strain, and this differential strain...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3547790/ https://ncbi.nlm.nih.gov/pubmed/23341783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003203 |
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