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ChIP-on-chip analysis identifies IL-22 as direct target gene of ectopically expressed FOXP3 transcription factor in human T cells

BACKGROUND: The transcription factor (TF) forkhead box P3 (FOXP3) is constitutively expressed at high levels in naturally occurring CD4(+)CD25(+) regulatory T cells (nTregs). It is not only the most accepted marker for that cell population but is also considered lineage determinative. Chromatin immu...

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Main Authors: Jeron, Andreas, Hansen, Wiebke, Ewert, Franziska, Buer, Jan, Geffers, Robert, Bruder, Dunja
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547697/
https://ncbi.nlm.nih.gov/pubmed/23244505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-705
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