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Isolation and preliminary characterization of temperature-sensitive mutants of measles virus.

Twenty-four genetically stable temperature-sensitive mutants of measles virus were isolated after mutangenesis by 5-azacytidine, 5 fluorouracil, or proflavine. The restricted replication of all mutants at 39 C was blocked subsequent to cell penetration and could not be attributed to heat inactivatio...

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Опубликовано в::J Virol
Главные авторы: Haspel, M V, Duff, R, Rapp, F
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1975
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC354762/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/51932/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.16.4.1000-1009.1975
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