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Painting Proteins Blue: β-(1-Azulenyl)-L-Alanine as a Probe for Studying Protein-Protein Interactions

We demonstrated that β-(1-Azulenyl)-L-Alanine, a fluorescent pseudoisosteric analog of tryptophan, exhibits weak environmental dependence and thus allows for using weak intrinsic quenchers, such as methionines, to monitor protein-protein interactions while not perturbing them.

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Detalhes bibliográficos
Main Authors: Moroz, Yurii S., Binder, Wolfgang, Nygren, Patrik, Caputo, Gregory A., Korendovych, Ivan V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547328/
https://ncbi.nlm.nih.gov/pubmed/23207368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc37550h
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