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Store-operated channels regulate intracellular calcium in mammalian rods

Exposure to daylight closes cyclic nucleotide-gated (CNG) and voltage-operated Ca(2+)-permeable channels in mammalian rods. The consequent lowering of the cytosolic calcium concentration ([Ca(2+)](i)), if protracted, can contribute to light-induced damage and apoptosis in these cells. We here report...

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Detalhes bibliográficos
Main Authors: Molnar, Tünde, Barabas, Peter, Birnbaumer, Lutz, Punzo, Claudio, Kefalov, Vladimir, Križaj, David
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547263/
https://ncbi.nlm.nih.gov/pubmed/22674725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.234641
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