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TLR agonists are highly effective at eliciting functional memory CTLs of effector memory phenotype in peptide immunization

Given the importance of memory cytotoxic T lymphocytes (CTLs) in eliminating altered self-cells, including virus-infected and tumor cells, devising effective vaccination strategies for generating memory CTLs is a priority in the field of immunology. Herein, we elaborate upon a novel boosting approac...

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Hlavní autoři: Smyth, Kendra, Garcia, Karla, Sun, Zhifeng, Tuo, Wenbin, Xiao, Zhengguo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547159/
https://ncbi.nlm.nih.gov/pubmed/23159338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2012.10.019
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