The association of down-regulated toll-like receptor 4 expression with airflow limitation and emphysema in smokers

BACKGROUND: An association between innate immunity including Toll-like receptors (TLRs) and COPD is reported recently; TLR4 deficiency in lung can cause emphysema in animals, which is not evident in humans. We analyzed the association of TLR4 expression, airflow limitation and emphysema in smokers....

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Hlavní autoři: Lee, Sei Won, Kim, Dal Rae, Kim, Tae Jung, Paik, Jin Ho, Chung, Jin-Haeng, Jheon, Sanghoon, Huh, Jin Won, Lee, Jae-Ho, Lee, Choon-Taek
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546871/
https://ncbi.nlm.nih.gov/pubmed/23170858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-13-106
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