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Form Follows Function: Structural and Catalytic Variation in the Class A Flavoprotein Monooxygenases

Flavoprotein monooxygenases (FPMOs) exhibit an array of mechanistic solutions to a common chemical objective; the monooxygenation of a target substrate. Each FPMO efficiently couples reduction of a flavin cofactor by NAD(P)H to oxygenation of the target substrate via a (hydro)peroxyflavin intermedia...

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Autors principals: Crozier-Reabe, Karen, Moran, Graham R.
Format: Artigo
Idioma:Inglês
Publicat: Molecular Diversity Preservation International (MDPI) 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546652/
https://ncbi.nlm.nih.gov/pubmed/23443084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131215601
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