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Temperature-sensitive mutants of herpes simplex virus type 1 defective in lysis but not in transformation.

Twelve temperature-sensitive (ts) mutants of herpes simplex virus type 1 (HSV-1), representing seven complementation groups, were isolated subsequent to 5-bromodeoxyuridine mutagenesis. These mutants were identified by their inability to replicate in a line of monkey (CV-1) cells at 39 C. Seven of t...

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Main Authors: Hughes, R G, Munyon, W H
格式: Artigo
語言:Inglês
出版: 1975
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC354665/
https://ncbi.nlm.nih.gov/pubmed/168402
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