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Using an experimental medicine model to understand the antidepressant potential of the N-Methyl-D-aspartic acid (NMDA) receptor antagonist memantine

There is growing interest in the role of the glutamatergic system both in depression and as a novel target for treatments. Preclinical studies suggested that the non-competitive N-Methyl-D-aspartic acid (NMDA) receptor antagonist memantine might have antidepressant properties, but a randomised contr...

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Detalhes bibliográficos
Main Authors: Pringle, A, Parsons, E, Cowen, LG, McTavish, SF, Cowen, PJ, Harmer, CJ
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546643/
https://ncbi.nlm.nih.gov/pubmed/22596208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881112446535
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