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Effect of 2-deoxy-D-glucose on herpesvirus-induced inhibition of cellular DNA synthesis.

In pseudorabies virus-infected cells host DNA synthesis is turned off 4 to 5 h postinfection. In the presence of 0.5 mM 2-deoxy-D-glucose, however, synthesis of both cellular and viral DNA proceeds unimpaired throughout the virus replication cycle. The uptake of radioactive thymidine into mock-infec...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Ludwig, H, Rott, R
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1975
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC354657/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/168399/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.16.2.217-221.1975
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