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Structure of the Human Metapneumovirus Fusion Protein with Neutralizing Antibody Identifies a Pneumovirus Antigenic Site
Human metapneumovirus (HMPV) and respiratory syncytial virus (RSV) cause lower respiratory infections. The virus fusion (F) glycoprotein promotes membrane fusion by refolding from a metastable pre-fusion to a stable post-fusion conformation. F is also a major target of the neutralizing antibody resp...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3546531/ https://ncbi.nlm.nih.gov/pubmed/22388735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2250 |
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