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Anatomy of herpes simplex virus DNA. III. Characterization of defective DNA molecules and biological properties of virus populations containing them.

We have characterized the virus progeny and its DNA from plaque-purified and undiluted passages of herpes simplex virus 1 in HEp-2 cells. Secifically, (i) infectious virus yields declined progressively in passages 1 through 10 and gradually increased at passages 11 through 14. The yields correlated...

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Autors principals: Frenkel, N, Jacob, R J, Honess, R W, Hayward, G S, Locker, H, Roizman, B
Format: Artigo
Idioma:Inglês
Publicat: 1975
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC354644/
https://ncbi.nlm.nih.gov/pubmed/166202
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