Poly(I:C)/Alum Mixed Adjuvant Priming Enhances HBV Subunit Vaccine-Induced Immunity in Mice When Combined with Recombinant Adenoviral-Based HBV Vaccine Boosting

BACKGROUND: Virus-specific cellular immune responses play a critical role in virus clearance during acute or chronic HBV infection. Currently, the commercially available HBV vaccine is combined with alum adjuvant, which stimulates mainly Th2 immune responses. Therefore, development of new therapeuti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chuai, Xia, Chen, Hong, Wang, Wen, Deng, Yao, Wen, Bo, Ruan, Li, Tan, Wenjie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545998/
https://ncbi.nlm.nih.gov/pubmed/23335993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054126
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