Mutagenicity and antimutagenicity of (−)-hinokinin a trypanosomicidal compound measured by Salmonella microsome and comet assays

BACKGROUND: The dibenzylbutyrolactone lignan (−)-hinokinin (HK) was derived by partial synthesis from (−)-cubebin, isolated from the dry seeds of the pepper, Piper cubeba. Considering the good trypanosomicidal activity of HK and recalling that natural products are promising starting points for the d...

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Bibliografiske detaljer
Main Authors: Resende, Flávia Aparecida, Barbosa, Lilian Cristina, Tavares, Denise Crispim, de Camargo, Mariana Santoro, de Souza Rezende, Karen Cristina, e Silva, Márcio Luis de Andrade, Varanda, Eliana Aparecida
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545969/
https://ncbi.nlm.nih.gov/pubmed/23114276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-12-203
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