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Differential lumbar spinal cord responses among wild type, CD4 knockout, and CD40 knockout mice in spinal nerve L5 transection-induced neuropathic pain

BACKGROUND: Our previous studies have indicated that both lumbar spinal cord-infiltrating CD4(+) T cells and microglial CD40 contribute to the maintenance of mechanical hypersensitivity in a murine model of neuropathic pain spinal nerve L5 transection (L5Tx). To further delineate the CD4 and CD40-me...

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Autors principals: Cao, Ling, Beaulac, Holly, Eurich, Adriana
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545955/
https://ncbi.nlm.nih.gov/pubmed/23249743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-88
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