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Interleukin-7 receptor controls development and maturation of late stages of thymocyte subpopulations

Interleukin (IL)-7 is a cytokine essential for T lymphocyte development and homeostasis. However, little is known about the roles of IL-7 receptor α-chain (IL-7Rα) in late stages of T-cell development. To address this question, we established IL-7Rα–floxed mice and crossed them with CD4-Cre transgen...

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Hlavní autoři: Tani-ichi, Shizue, Shimba, Akihiro, Wagatsuma, Keisuke, Miyachi, Hitoshi, Kitano, Satsuki, Imai, Kumiko, Hara, Takahiro, Ikuta, Koichi
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545802/
https://ncbi.nlm.nih.gov/pubmed/23267098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219242110
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