Reverse-engineering the genetic circuitry of a cancer cell with predicted intervention in chronic lymphocytic leukemia

Cellular behavior is sustained by genetic programs that are progressively disrupted in pathological conditions—notably, cancer. High-throughput gene expression profiling has been used to infer statistical models describing these cellular programs, and development is now needed to guide orientated mo...

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Autori principali: Vallat, Laurent, Kemper, Corey A., Jung, Nicolas, Maumy-Bertrand, Myriam, Bertrand, Frédéric, Meyer, Nicolas, Pocheville, Arnaud, Fisher, John W., Gribben, John G., Bahram, Seiamak
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545767/
https://ncbi.nlm.nih.gov/pubmed/23267079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211130110
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