Historical variations in mutation rate in an epidemic pathogen, Yersinia pestis

The genetic diversity of Yersinia pestis, the etiologic agent of plague, is extremely limited because of its recent origin coupled with a slow clock rate. Here we identified 2,326 SNPs from 133 genomes of Y. pestis strains that were isolated in China and elsewhere. These SNPs define the genealogy of...

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Hoofdauteurs: Cui, Yujun, Yu, Chang, Yan, Yanfeng, Li, Dongfang, Li, Yanjun, Jombart, Thibaut, Weinert, Lucy A., Wang, Zuyun, Guo, Zhaobiao, Xu, Lizhi, Zhang, Yujiang, Zheng, Hancheng, Qin, Nan, Xiao, Xiao, Wu, Mingshou, Wang, Xiaoyi, Zhou, Dongsheng, Qi, Zhizhen, Du, Zongmin, Wu, Honglong, Yang, Xianwei, Cao, Hongzhi, Wang, Hu, Wang, Jing, Yao, Shusen, Rakin, Alexander, Li, Yingrui, Falush, Daniel, Balloux, Francois, Achtman, Mark, Song, Yajun, Wang, Jun, Yang, Ruifu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2013
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545753/
https://ncbi.nlm.nih.gov/pubmed/23271803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205750110
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