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Amphipathic antenna of an inward rectifier K(+) channel responds to changes in the inner membrane leaflet
Membrane lipids modulate the function of membrane proteins. In the case of ion channels, they bias the gating equilibrium, although the underlying mechanism has remained elusive. Here we demonstrate that the N-terminal segment (M0) of the KcsA potassium channel mediates the effect of changes in the...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545751/ https://ncbi.nlm.nih.gov/pubmed/23267068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217323110 |
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