Glucocorticoid Repression of Inflammatory Gene Expression Shows Differential Responsiveness by Transactivation- and Transrepression-Dependent Mechanisms

Binding of glucocorticoid to the glucocorticoid receptor (GR/NR3C1) may repress inflammatory gene transcription via direct, protein synthesis-independent processes (transrepression), or by activating transcription (transactivation) of multiple anti-inflammatory/repressive factors. Using human pulmon...

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Main Authors: King, Elizabeth M., Chivers, Joanna E., Rider, Christopher F., Minnich, Anne, Giembycz, Mark A., Newton, Robert
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545719/
https://ncbi.nlm.nih.gov/pubmed/23349769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053936
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