Signal Transducers and Activators of Transcription-3/Pim1 Axis Plays a Critical Role in the Pathogenesis of Human Pulmonary Arterial Hypertension

BACKGROUND: Pulmonary artery hypertension (PAH) is a proliferative disorder associated with enhanced pulmonary artery smooth muscle cell proliferation and suppressed apoptosis. The sustainability of this phenotype required the activation of a prosurvival transcription factor like signal transducers...

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Hlavní autoři: Paulin, Roxane, Courboulin, Audrey, Meloche, Jolyane, Mainguy, Vincent, de la Roque, Eric Dumas, Saksouk, Nehmé, Côté, Jacques, Provencher, Steeve, Sussman, Mark A., Bonnet, Sébastien
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545712/
https://ncbi.nlm.nih.gov/pubmed/21382889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.110.963314
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