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Mitochondrial localization of P-glycoprotein and peptide transporters in corneal epithelial cells –Novel strategies for intracellular drug targeting

PURPOSE: This study was designed to investigate functional localization of both efflux (P-glycoprotein, P-gp) and influx (peptide) transporters in the mitochondrial membrane of cultured rabbit primary corneal epithelial cells (rPCECs). METHODS: Isolation and purification of mitochondria was performe...

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Bibliografiske detaljer
Main Authors: Barot, Megha, Gokulgandhi, Mitan R., Pal, Dhananjay, Mitra, Ashim K.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545686/
https://ncbi.nlm.nih.gov/pubmed/23116562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2012.10.006
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