Adrenomedullin gene dosage correlates with tumor and lymph node lymphangiogenesis

Adrenomedullin (AM) is a potent lymphangiogenic factor that promotes lymphatic endothelial cell (LEC) proliferation through a pharmacologically tractable G-protein-coupled receptor. Numerous types of human cancers have increased levels of AM; however, the functional consequences of this fact have no...

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Autors principals: Karpinich, Natalie O., Kechele, Daniel O., Espenschied, Scott T., Willcockson, Helen H., Fedoriw, Yuri, Caron, Kathleen M.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2013
Matèries:
Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545524/
https://ncbi.nlm.nih.gov/pubmed/23099649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-214080
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