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Dissecting the mechanisms of Notch induced hyperplasia
The outcome of the Notch pathway on proliferation depends on cellular context, being growth promotion in some, including several cancers, and growth inhibition in others. Such disparate outcomes are evident in Drosophila wing discs, where Notch overactivation causes hyperplasia despite having locali...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Molecular Biology Organization
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545308/ https://ncbi.nlm.nih.gov/pubmed/23232763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.326 |
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