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Binding determinants of the small heat shock protein, αB-crystallin: recognition of the ‘IxI’ motif

Small heat shock proteins (sHSPs) play a central role in protein homeostasis under conditions of stress by binding partly unfolded, aggregate-prone proteins and keeping them soluble. Like many sHSPs, the widely expressed human sHSP, αB-crystallin (‘αB’), forms large polydisperse multimeric assemblie...

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Detalhes bibliográficos
Main Authors: Delbecq, Scott P, Jehle, Stefan, Klevit, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545294/
https://ncbi.nlm.nih.gov/pubmed/23188086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.318
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