MLL Histone Methylases Regulate Expression of HDLR-SR-B1 in Presence of Estrogen and Control Plasma Cholesterol in Vivo

High-density lipoprotein receptors scavenger receptor class B type I [HDLR-SR-B1 (SR-B1)] is a key player in reverse cholesterol transport and maintaining blood cholesterol. We demonstrated that human SR-B1 is transcriptionally activated by 17β-estradiol (E2) in HEPG2 and JAR cells. SR-B1 promoter c...

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Main Authors: Ansari, Khairul I., Kasiri, Sahba, Hussain, Imran, Bobzean, Samara A. Morris, Perrotti, Linda I., Mandal, Subhrangsu S.
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2013
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545218/
https://ncbi.nlm.nih.gov/pubmed/23192982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1147
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