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Influenza virion RNA-dependent RNA polymerase: stimulation by guanosine and related compounds.

The activity of RNA-dependent RNA polymerase of several influenza viruses is stimulated by guanosine. Depending upon the virus strain used, the stimulation of initial reaction rate is up to 10-fold. 5'-GMP, 3',5'-cyclic GMP, and 5'-GDP show lesser stimulation effects. No other nucleosides of 5'-NMPs...

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Bibliographic Details
Published in:J Virol
Main Authors: McGeoch, D, Kitron, N
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1975
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC354510/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/163915/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.15.4.686-695.1975
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