Apolipoprotein E and Familial Longevity

BACKGROUND: Exceptional longevity is associated with substantial heritability. The ε4 allele in Apolipoprotein E and the linked G allele in rs2075650 of TOMM40 have been associated with increased mortality and the ε2 allele with decreased mortality, although inconsistently. METHODS: Offspring from l...

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Detalhes bibliográficos
Main Authors: Schupf, Nicole, Barral, Sandra, Perls, Thomas, Newman, Anne, Christensen, Kaare, Thyagarajan, Bharat, Province, Michael, Rossi, Winifred K, Mayeux, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545094/
https://ncbi.nlm.nih.gov/pubmed/23040522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2012.08.019
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