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The Binding of Antibiotics in OmpF Porin

The structure of OmpF porin in complex with three common antibiotics (zwitterionic ampicillin, anionic ertapenem, and di-anionic carbenicillin) was determined using X-ray crystallography. The three antibiotics are found to bind within the extracellular and periplasmic pore vestibules, away from the...

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Bibliografske podrobnosti
Main Authors: Ziervogel, Brigitte K., Roux, Benoît
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545085/
https://ncbi.nlm.nih.gov/pubmed/23201272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.10.014
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