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The Binding of Antibiotics in OmpF Porin
The structure of OmpF porin in complex with three common antibiotics (zwitterionic ampicillin, anionic ertapenem, and di-anionic carbenicillin) was determined using X-ray crystallography. The three antibiotics are found to bind within the extracellular and periplasmic pore vestibules, away from the...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545085/ https://ncbi.nlm.nih.gov/pubmed/23201272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.10.014 |
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