Pharmacodynamic interplay of the P2Y(1), P2Y(12), and TxA(2) pathways in platelets: the potential of triple antiplatelet therapy with P2Y(1) receptor antagonism

INTRODUCTION: Previous work suggests that the extent of platelet inhibition by P2Y(1) receptor antagonism may be underappreciated, particularly in the context of dual antiplatelet therapy with aspirin and clopidogrel. MATERIALS AND METHODS: Using P2Y(1), P2Y(12), and TxA(2) receptor antagonists indi...

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Main Authors: Oestreich, Julie H., Ferraris, Suellen P., Steinhubl, Steven R., Akers, Wendell S.
格式: Artigo
語言:Inglês
出版: 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545076/
https://ncbi.nlm.nih.gov/pubmed/23245937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2012.11.019
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