Flavonoids inhibit the platelet TxA(2) signalling pathway and antagonize TxA(2) receptors (TP) in platelets and smooth muscle cells

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: Flavonoids are largely recognized as potential inhibitors of platelet function, through nonspecific mechanisms such as antioxidant activity and/or inhibition of several enzymes and signalling proteins. In addition, we, and few others, have shown that certain...

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Main Authors: Guerrero, José A, Navarro-Nuñez, Leyre, Lozano, María L, Martínez, Constantino, Vicente, Vicente, Gibbins, Jonathan M, Rivera, José
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2007
Teme:
Pharmacokinetics & Pharmacodynamics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000638/
https://ncbi.nlm.nih.gov/pubmed/17425630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02881.x
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