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Pharmacodynamic interplay of the P2Y(1), P2Y(12), and TxA(2) pathways in platelets: the potential of triple antiplatelet therapy with P2Y(1) receptor antagonism

INTRODUCTION: Previous work suggests that the extent of platelet inhibition by P2Y(1) receptor antagonism may be underappreciated, particularly in the context of dual antiplatelet therapy with aspirin and clopidogrel. MATERIALS AND METHODS: Using P2Y(1), P2Y(12), and TxA(2) receptor antagonists indi...

詳細記述

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書誌詳細
主要な著者: Oestreich, Julie H., Ferraris, Suellen P., Steinhubl, Steven R., Akers, Wendell S.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545076/
https://ncbi.nlm.nih.gov/pubmed/23245937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2012.11.019
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