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Decreased afferent excitability contributes to synaptic depression during high-frequency stimulation in hippocampal area CA1

Long-term potentiation (LTP) is often induced experimentally by continuous high-frequency afferent stimulation (HFS), typically at 100 Hz for 1 s. Induction of LTP requires postsynaptic depolarization and voltage-dependent calcium influx. Induction is more effective if the same number of stimuli are...

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Detalles Bibliográficos
Main Authors: Kim, Eunyoung, Owen, Benjamin, Holmes, William R., Grover, Lawrence M.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544996/
https://ncbi.nlm.nih.gov/pubmed/22773781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00276.2011
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