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Laser Capture Microdissected Mucosa versus Whole Tissue Specimens for Assessment of Radiation-Induced Dynamic Molecular and Pathway Changes in the Small Intestine

BACKGROUND: The intestinal mucosa is the compartment that sustains the most severe injury in response to radiation and is therefore of primary interest. The use of whole gut extracts for analysis of gene expression may confound important changes in the mucosa. On the other hand, laser capture microd...

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Detalhes bibliográficos
Main Authors: Zheng, Junying, Garg, Sarita, Wang, Junru, Loose, David S., Hauer-Jensen, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544848/
https://ncbi.nlm.nih.gov/pubmed/23341980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053711
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