Method for determination of nucleotide sequence homology between viral genomes by DNA reassociation kinetics.

A model and appropriate equations were derived for the quantitative estimation of nucleotide sequence homology between two partially related viral genomes by measurement of the initial rate of reassociation of one labeled DNA in the presence of a second unlabeled DNA. The validity and usefulness of...

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Bibliographic Details
Main Authors: Fujinaga, K, Sekikawa, K, Yamazaki, H
Format: Artigo
Language:Inglês
Published: 1975
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC354481/
https://ncbi.nlm.nih.gov/pubmed/1113376
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