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The mutated staphylococcal H35A α-toxin inhibits adhesion and invasion of Staphylococcus aureus and group A streptococci

In previous studies we demonstrated that the staphylococcal α-toxin inhibits adhesion and invasion of S. aureus by epithelial cells through binding to α5β1 integrin, a receptor of fibronectin. Moreover, we revealed that a H35A mutation abolishes the cytotoxicity of α-toxin completely. These findings...

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Hlavní autoři: Yang, Junshu, Liang, Xudong, Ji, Yinduo
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544751/
https://ncbi.nlm.nih.gov/pubmed/23314570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/viru.22719
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