Dose-dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin-like growth factor-1

The prevalence of obesity, an established risk and progression factor for breast and many other cancer types, remains very high in the United States and throughout the world. Calorie restriction (CR), a reduced-calorie dietary regimen typically involving a 20–40% reduction in calorie consumption, pr...

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Bibliographic Details
Main Authors: Nogueira, Leticia M, Lavigne, Jackie A, Chandramouli, Gadisetti V R, Lui, Huaitian, Barrett, J Carl, Hursting, Stephen D
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2012
Subjects:
Cancer Prevention
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544443/
https://ncbi.nlm.nih.gov/pubmed/23342276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.23
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