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Periadolescent Exposure to the NMDA Receptor Antagonist MK-801 Impairs the Functional Maturation of Local GABAergic Circuits in the Adult Prefrontal Cortex

A developmental disruption of prefrontal cortical inhibitory circuits is thought to contribute to the adolescent onset of cognitive deficits observed in schizophrenia. However, the developmental mechanisms underlying such a disruption remain elusive. The goal of this study is to examine how repeated...

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Autori principali: Thomases, Daniel R., Cass, Daryn K., Tseng, Kuei Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544161/
https://ncbi.nlm.nih.gov/pubmed/23283319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4147-12.2013
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