Notch2 regulates matrix metallopeptidase 9 via PI3K/AKT signaling in human gastric carcinoma cell MKN-45

AIM: To clarify the role of activated Notch2 in the invasiveness of gastric cancer. METHODS: To investigate the invasiveness of silencing Notch2 gene expression, we established a Notch2 small interfering RNA (siRNA) transfected cell line using the MKN-45 gastric cancer cell line. After the successfu...

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Hlavní autoři: Guo, Ling-Yun, Li, Yu-Min, Qiao, Liang, Liu, Tao, Du, Yuan-Yuan, Zhang, Jun-Qiang, He, Wen-Ting, Zhao, Yong-Xun, He, Dong-Qiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Co., Limited 2012
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544028/
https://ncbi.nlm.nih.gov/pubmed/23326131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i48.7262
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