Transcriptional and post-transcriptional regulation of cGMP-dependent protein kinase (PKG-I): pathophysiological significance

The ability of the endothelium to produce nitric oxide, which induces generation of cyclic guanosine monophosphate (cGMP) that activates cGMP-dependent protein kinase (PKG-I), in vascular smooth muscle cells (VSMCs), is essential for the maintenance of vascular homeostasis. Yet, disturbance of this...

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Hlavní autoři: Sellak, Hassan, Choi, Chung-sik, Dey, Nupur B., Lincoln, Thomas M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
Topical Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543991/
https://ncbi.nlm.nih.gov/pubmed/23139241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs327
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